Zyban (Bupropion Hydrochloride)

Quitting Smoking : Zyban

Like Nicotine Replacement Therapies, Zyban has been proven to double a smokers chance of quitting successfully.

Please note that at the time of writing Zyban is only available on prescription in the UK. Your GP will be able to advise you if Zyban is the most suitable smoking cessation product for you.

Zyban was originally an anti-depressant called Wellbutrin (bupropion hydrochloride). Smokers who were using Wellbutrin reported that they were no longer craving cigarettes. After further clinical tests the drug was found to be useful in helping smokers quit so was rebranded Zyban.

Zyban has proved to be a highly effective method for quitting smoking. It is a non nicotine tablet which works by de-sensitising the brains nicotine receptors. It makes smoking less pleasurable and reduces craving while you work on your smoking habits.

You start taking Zyban while you are still smoking and set a date for quitting during the second week of treatment. A course of Zyban tablets lasts two months and doubles your chances of quitting smoking successfuly.

Zyban may be a good choice for people who prefer an alternative to nicotine replacement, or who have not succeeded on traditional nicotine replacement therapies.

There are side effects with Zyban, the most common being headaches, difficulty sleeping and suffering from a dry mouth. Around 30% of users suffer from these. There is also a risk of seizure, which is the same level of risk as that of other similar drugs in the anti-depressant family (1 in 1000).

The GlaxoSmithKline patient information leaflet can be found here.

Due to the side effects experienced with Zyban, it is suggested that you seeking professional medical advice before using the product.